Ok, I found this one this morning and just thought it was cool. Select some text (using whatever method you desire), hold CTRL and Shift and press either < or > to decrease or increase the font size. This works in Microsoft Word, Outlook, and probably other Microsoft programs as well. I tried it in OpenOffice Writer and it did’t work there however.
Along similar lines, while in a web browser you can hold CTRL and press + or – to increase the font size that is being displayed.